الصفحة الرئيسية>>ODN 24888

ODN 24888

رقم الكتالوجGC71137

ODN 24888 هو الأوليغنوكليوتيدات المثبطة المعدلة جوانين (INH-ODN)، ويظهر تثبيط قوي على إشارات TLR7/TLR9.

Products are for research use only. Not for human use. We do not sell to patients.

ODN 24888 التركيب الكيميائي

Cas No.: 1964506-30-6

الحجم السعر المخزون الكميّة
1 mg
281٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ODN 24888 is an guanine-modified inhibitory oligonucleotides (INH-ODN), shows potent inhibition on TLR7/TLR9-mediated signaling. ODN 24888 impairs IFN-α level and NF-κB activation, inhibits IL-6 release. ODN 24888 involves in immune and inflammatory responses, can be used as a vaccine adjuvant.

References:
[1]. Saul Meike, et al. Reduction of bone resorption, especially in chronic joint diseases: Germany, DE102019122014 A1. 2021-02-18.
[2]. Römmler F, et al. Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated im mune responses of human immune cells. PLoS One. 2015 Feb 19;10(2):e0116703.

مراجعات

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