OICR-0547 |
| رقم الكتالوجGC33021 |
OICR-0547 هو مشتق وثيق الصلة بـ OICR-9429OICR-9429 هو مضاد جديد لجزيء صغير لتفاعل Wdr5-MLL ، بينما OICR-0547 هو مركب تحكم غير نشط لم يعد يرتبط بـ WDR5
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Cas No.: 1801873-49-3
Sample solution is provided at 25 µL, 10mM.
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OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction, while OICR-0547 cannot bind to WDR5.
[1]. Grebien F, et al. Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia. Nat Chem Biol. 2015 Aug;11(8):571-578.
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