Osanetant |
| رقم الكتالوجGC38829 |
Osanetant (SR142801) هو مضاد انتقائي لمستقبلات NK3
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 160492-56-8
Sample solution is provided at 25 µL, 10mM.
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Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for the treatment of schizophrenia[1].
Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time[1]. Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time[1]. Animal Model: Male Mongolian gerbils of 7 weeks old (50-60 g)[1]
[1]. SalomÉ N, et al. Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. Pharmacol Biochem Behav. 2006 Apr;83(4):533-9.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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