Pabinafusp alfa |
| رقم الكتالوجGC72441 |
Pabinafusp alfa (JR-141) هو جسم مضاد يستهدف مستقبلات الترانسفيرين يتكون من إيدورونات 2-سلفاتاز وجسم مضاد لمستقبلات الترانسفيرين البشرية.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2140211-48-7
Sample solution is provided at 25 µL, 10mM.
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Pabinafusp alfa (0.1-2 mg/kg; i.v.; once weekly for 36 weeks) dose-dependently prevents neurohistopathological changes and ameliorates neurological defects in a mouse model of MPS II[1].
References:
[1]. Morimoto H, et al. Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice. Mol Ther Methods Clin Dev. 2022 May 10;25:534-544.
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