Phosphoramidon (Synonyms: N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan•2Na) |
رقم الكتالوجGB40322 |
Phosphoramidon (119942-99-3) inhibits neutral endopeptidase 24.11 (NEP; Neprilysin; EC 3.4.24.11), Ki=2 nM. Also inhibits neprilysin 2 (Ki~2 nM). Also inhibits endothelin-converting enzyme (IC50 = 0.68 μM). Induces a dramatic increase in amyloid-beta levels in rodents.
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Cas No.: 119942-99-3
Sample solution is provided at 25 µL, 10mM.
Phosphoramidon (119942-99-3) inhibits neutral endopeptidase 24.11 (NEP; Neprilysin; EC 3.4.24.11), Ki=2 nM. Also inhibits neprilysin 2 (Ki~2 nM). Also inhibits endothelin-converting enzyme (IC50 = 0.68 μM). Induces a dramatic increase in amyloid-beta levels in rodents.
Average Rating: 5
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