Pinane Thromboxane A2 (Synonyms: 15(S)-Pinane Thromboxane A2, Pinane TXA2, PTA2) |
رقم الكتالوجGC41174 |
Pinane thromboxane A2 (PTA2) is a stable analog of TXA2.
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Cas No.: 71111-01-8
Sample solution is provided at 25 µL, 10mM.
Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. It is a TP receptor antagonist and an inhibitor of thromboxane synthase. PTA2 inhibits U-46619-induced cat coronary artery constriction (ID50 = 0.1 µM), U-46619-induced aggregation of human platelets (IC50 = 2 µM), and rabbit platelet thromboxane synthase (ID50 = 50 µM). PTA2 does not affect PGI synthase up to a concentration of 100 µM.
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