Posaconazole-d5 |
| رقم الكتالوجGC90195 |
معيار داخلي لتحديد كمية بوساكونازول
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2649530-57-2
Sample solution is provided at 25 µL, 10mM.
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Posaconazole-d5 is intended for use as an internal standard for the quantification of posaconazole by GC- or LC-MS. Posaconazole is a broad-spectrum triazole antifungal agent active against various yeasts and molds, including Aspergillus, Candida, Fusarium, and Zygomycetes.1 Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14α-demetlase enzyme (IC50s = 7-200 nM), which results in a disruption in the synthesis of ergosterol , a key sterol necessary for fungal cell membrane integrity and for the function of certain membrane-bound proteins.2
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