الصفحة الرئيسية>>Lipids>> Prostaglandins>>Prostaglandin G2

Prostaglandin G2 (Synonyms: PGG2)

رقم الكتالوجGC18390

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized.

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Prostaglandin G2 التركيب الكيميائي

Cas No.: 51982-36-6

الحجم السعر المخزون الكميّة
500μg
1975٫00
متوفر
25μg
126٫00
متوفر
50μg
237٫00
متوفر
100μg
444٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of Prostaglandin G2

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key precursor to the 2-series PGs and thromboxanes.

Chemical Properties of Prostaglandin G2

Cas No. 51982-36-6 SDF
المرادفات PGG2
Chemical Name 9α,11α-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid
Canonical SMILES CCCCC[C@@H](OO)/C=C/[C@H]1[C@@H]2OO[C@@H](C2)[C@H]1C/C=C\CCCC(O)=O
Formula C20H32O6 M.Wt 368.5
الذوبان DMF: DO NOT USE DMF,DMSO: DO NOT USE DMSO,Ethanol: >100 mg/ml (from U-46619),PBS pH 7.2: >2 mg/ml (from U-46619) Storage Store at -80°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Prostaglandin G2

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.7137 mL 13.5685 mL 27.137 mL
5 mM 0.5427 mL 2.7137 mL 5.4274 mL
10 mM 0.2714 mL 1.3569 mL 2.7137 mL
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In vivo Formulation Calculator (Clear solution) of Prostaglandin G2

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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