الصفحة الرئيسية>>Lipids>> Prostaglandins>>Prostaglandin K2

Prostaglandin K2 (Synonyms: PGK2)

رقم الكتالوجGC18753

Prostaglandin K2 (PGK2) is the 9,11-diketone formed by the oxidation of PGE2 or PGD2.

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Prostaglandin K2 التركيب الكيميائي

Cas No.: 275816-51-8

الحجم السعر المخزون الكميّة
500μg
295٫00
متوفر
100μg
67٫00
متوفر
1mg
523٫00
متوفر
5mg
2279٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of Prostaglandin K2

Prostaglandin K2 (PGK2) is the 9,11-diketone formed by the oxidation of PGE2 or PGD2. Whether this compound exists biologically is uncertain; it is known to be resistant to metabolism by 15-hydroxy PGDH in vitro.

Chemical Properties of Prostaglandin K2

Cas No. 275816-51-8 SDF
المرادفات PGK2
Chemical Name 9,11-dioxo-15S-hydroxy-prosta-5Z,13E-dien-1-oic acid
Canonical SMILES O=C(C1)[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C1=O
Formula C20H30O5 M.Wt 350.5
الذوبان DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12, Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Prostaglandin K2

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8531 mL 14.2653 mL 28.5307 mL
5 mM 0.5706 mL 2.8531 mL 5.7061 mL
10 mM 0.2853 mL 1.4265 mL 2.8531 mL
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In vivo Formulation Calculator (Clear solution) of Prostaglandin K2

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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