QPX7728-OH disodium (Synonyms: QPX7728 disodium) |
| رقم الكتالوجGC62237 |
Xeruborbactam (QPX7728) ثنائي الصوديوم هو مثبط قوي واسع الطيف لحمض البورونيك بيتا لاكتاماز.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2170848-99-2
Sample solution is provided at 25 µL, 10mM.
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QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin by purified class A, C and D enzymes, with Kis less than 0.1 µμ[1].
QPX7728-OH disodium potentiates Aztreonam and Tigemonam against strains expressing class A and class C enzymes, with MICs≤5 µg/mL. QPX7728-OH disodium potentiates Biapenem against strains expressing class A (KPC) or class D (OXA-48) carbapenemases, with MICs≤5 µg/mL[1].
[1]. Scott Hecker, et al. Boronic acid derivatives and therapeutic uses thereof. WO2018005662A1.
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