الصفحة الرئيسية>>Signaling Pathways>> Others>> Mineralocorticoid Receptor>>(Rac)-Finerenone

(Rac)-Finerenone (Synonyms: (Rac)-BAY 94-8862)

رقم الكتالوجGC62332

(Rac) -Finerenone ((Rac) -BAY 94-8862) هو رفاق سباق Finerenone

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(Rac)-Finerenone التركيب الكيميائي

Cas No.: 1050477-27-4

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
297٫00
متوفر
5 mg
270٫00
متوفر
10 mg
432٫00
متوفر
25 mg
855٫00
متوفر
50 mg
1305٫00
متوفر
100 mg
2025٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

(Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold)[1].

[1]. BÄrfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403.

مراجعات

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