RBP4 inhibitor 1 |
| رقم الكتالوجGC70877 |
RBP4 inhibitor 1 (مركب 43b) هو مثبط بروتين ربط الريتينول 4 (RBP4) الفعال والفموي مع IC50s من 28 نانومتر و 110 نانومتر للبشر والفئران RBP4.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1198180-03-8
Sample solution is provided at 25 µL, 10mM.
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RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice.
References:
[1]. Shinji Nakamura, et al. Discovery of phenylpyrrolidine derivatives as a novel class of retinol binding protein 4 (RBP4) reducers. Bioorg Med Chem. 2022 Jan 15;54:116553.
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