δ12-Prostaglandin J2 (Synonyms: Δ12PGJ2) |
رقم الكتالوجGC41109 |
δ؛ 12-Prostaglandin J2 (δ؛ 12-PGJ2) عبارة عن سيكلوبنتينون بروستاغلاندين (PG) له تأثير مضاد للتكاثر على نمو خلايا الورم المختلفة. δ ؛ 12-Prostaglandin J2 ، وهو منتج طبيعي للجفاف من البروستاغلاندين D2 ، قادر على إحداث موت الخلايا المبرمج في خلايا هيلا عن طريق تنشيط كاسباس.
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Cas No.: 87893-54-7
Sample solution is provided at 25 µL, 10mM.
δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 µg/ml. δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand.
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