C16 Lactosylceramide (d18:1/16:0) (Synonyms: N-Hexadecanoyl Lactosylceramide, LacCer(d18:1/16:0), Lactosylceramide (d18:1/16:0), C16 Lactosyl(β) Ceramide (d18:1/16:0)) |
| رقم الكتالوجGC43033 |
C16 Lactosylceramide is an endogenous bioactive sphingolipid.
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Cas No.: 4201-62-1
Sample solution is provided at 25 µL, 10mM.
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C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle. C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.
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