C2 Galactosylceramide (d18:1/2:0) (Synonyms: Galactosylceramide (d18:1/2:0), GalCer(d18:1/2:0), β-Gal-C2-Cer, N-acetyl Psychosine) |
رقم الكتالوجGC43064 |
C2 Galactosylceramide (d18: 1/2: 0) (C2 Galactosylceramide (d18: 1/2: 0)) ، α ؛ -Galactosylated C2- سيراميد ، له نشاط مناعي.
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Cas No.: 35823-61-1
Sample solution is provided at 25 µL, 10mM.
C2 Galactosylceramide is a bioactive sphingolipid. It inhibits IL-4 production by 23.24% in EL4 T cells when used at a concentration of 10 μM. C2 Galactosylceramide stimulates NF-κB activity in C6 glioma cells and activates mast cells in a concentration-dependent manner. It is cytotoxic to U937 cells in vitro (IC50 = 33 μM). C2 Galactosylceramide also suppresses the allogeneic mixed leukocyte reaction (MLR) response in murine spleen cells in a concentration-dependent manner.
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