C2 L-erythro Ceramide (d18:1/2:0) (Synonyms: L-erythro Cer(d18:1/2:0), L-erythro Ceramide (d18:1/2:0), N-acetyl-L-erythro-Sphingosine) |
رقم الكتالوجGC40708 |
C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.
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Cas No.: 150338-90-2
Sample solution is provided at 25 µL, 10mM.
C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is >50% less than that stimulated by C2 ceramide . C2 L-erythro Ceramide also induces cell cycle arrest in the G0\G1 phase and a 50-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.,
Average Rating: 5
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