الصفحة الرئيسية>>Signaling Pathways>> PROTAC>>Cbz-NH-PEG1-CH2COOH

Cbz-NH-PEG1-CH2COOH

رقم الكتالوجGC60101

Cbz-NH-PEG1-CH2COOH عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تركيب PROTACs

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Cbz-NH-PEG1-CH2COOH التركيب الكيميائي

Cas No.: 1260092-43-0

الحجم السعر المخزون الكميّة
250mg
139٫00
متوفر
500mg
232٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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