Diflorasone Diacetate (Synonyms: U-34865) |
رقم الكتالوجGC40867 |
ثنائي أسيتات ديفلوراسون هو مركب ستيرويد مضاد للالتهابات يستخدم كعامل محلي أو موضعي
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Cas No.: 33564-31-7
Sample solution is provided at 25 µL, 10mM.
Diflorasone is a corticosteroid with anti-inflammatory activity. It reduces production of the inflammatory cytokines Il-6, Il-4, and macrophage inflammatory protein-2 (Mip-2) and completely inhibits swelling in the ears of toluene-2,4-diisocyaniate-sensitized mice following topical administration of 20 µL of a 0.05% solution. Diflorasone inhibits RANTES and thymus and activation regulated chemokine (TARC) in a dinitrochlorobenzene-induced mouse model of allergic contact dermatitis. It also inhibits proliferation of human keratinocytes in vitro and reduces epidermal thickening in a mouse model of psoriasis induced by imiquimod .
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