Dimetacrine (Dimethacrine) |
رقم الكتالوجGC31182 |
ديميتاكرين (ديميثاكرين) له تأثير مفيد مضاد للاكتئاب ، ويمكن استخدامه في البحث عن أنواع مختلفة من الاكتئاب.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4757-55-5
Sample solution is provided at 25 µL, 10mM.
Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression.
Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression. Dimetacrine in the highest concentration, 10 μM, decreases the contractile force to 36.5±9.1%. Dimetacrine, 0.3 μM, causes no statistically significant decline in contractile force from the controls. Tachycardia is observed after the administration of Dimetacrine, 1 to 3 mg/kg i.v., and the maximum response is obtained in dose of 3 mg/kg i.v.. The administration of Dimetacrine, 30 mg/kg i.v., causes an abrupt fall in blood pressure with tachycardia or bradycardia followed by cardiac arrest. Respiratory rate increases 40 min after the onset of infusion of Dimetacrine. Arterial blood pressure falls 50 min after the onset of infusion of Dimetacrine[1].
[1]. Kato H, et al. Comparison of cardiovascular toxicities induced by dimetacrine, imipramine and amitriptyline in isolated guinea pig atria and anesthetized dogs. Jpn J Pharmacol. 1974 Dec;24(6):885-91.
Average Rating: 5
(Based on Reviews and 22 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *