الصفحة الرئيسية>>Signaling Pathways>> Metabolism>> phosphatases>>F1063-0967

F1063-0967

رقم الكتالوجGC33227

F1063-0967 هو مثبط ثنائي النوعية من الفوسفاتيز 26 (DUSP26) مع IC50 يبلغ 11.62 ميكرومتر

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F1063-0967 التركيب الكيميائي

Cas No.: 613225-56-2

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
55٫00
متوفر
5mg
50٫00
متوفر
10mg
81٫00
متوفر
50mg
225٫00
متوفر
100mg
315٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.

F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. At concentration above 0.1 μM, F1063-0967 remarkably induces IMR32 cell apoptosis. F1063-0967 induces apoptosis in IMR-32 cell line with an IC50 value of 4.13 μM. F1063-0967 has no effect on HL7702 cell line, and little inhibition effect on SH-SY5Y cell line[1].

[1]. Ren JX, et al. Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular docking. Biomed Pharmacother. 2017 May;89:376-385.

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