FW1256 |
رقم الكتالوجGC39382 |
FW1256 هو نظير فينيل ومانح بطيء الإطلاق لكبريتيد الهيدروجين (H2S)
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Cas No.: 117089-08-4
Sample solution is provided at 25 µL, 10mM.
FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activities and induces cell apoptosis. FW1256 has the potential for cancer, inflammation, and cardiovascular disease treatment[1][2].
[1]. Huang CW, et al. A novel slow-releasing hydrogen sulfide donor, FW1256, exerts anti-inflammatory effects in mouse macrophages and in vivo. Pharmacol Res. 2016 Nov;113(Pt A):533-546. [2]. Feng W, et al. Discovery of New H2S Releasing Phosphordithioates and 2,3-Dihydro-2-phenyl-2-sulfanylenebenzo[d][1,3,2]oxazaphospholes with Improved Antiproliferative Activity. J Med Chem. 2015 Aug 27;58(16):6456-80.
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