BMS-962212 |
| رقم الكتالوجGC35536 |
BMS-962212 هو مثبط مباشر وقابل للعكس وانتقائي للعامل XIa (FXIa)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1430114-34-3
Sample solution is provided at 25 µL, 10mM.
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BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1].
[1]. Perera V, et al. First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects. Br J Clin Pharmacol. 2018 May;84(5):876-887.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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