CDK4/6-IN-2 |
| رقم الكتالوجGC35633 |
CDK4 / 6-IN-2 عبارة عن مثبط قوي لـ CDK4 و CDK6 مستخرج من براءة الاختراع US20180000819A1 ، المركب 1 ، يحتوي على IC50s من 2.7 و 16 نانومتر لـ CDK4 و CDK6 ، على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1800506-48-2
Sample solution is provided at 25 µL, 10mM.
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CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively[1]. CDK4|2.7 nM (IC50)|CDK6|16 nM (IC50)
CDK4/6-IN-2 inhibits H358, H441, PC3, MV-4-11, JeKo-1, SW780, and HGC-27 cells with IC50s of 290.9, 147.8, 260.5, 139, 36.98, 162.5, and 316.4 nM, respectively[1].
[1]. Frank Wu, et al. Kinase inhibitor and use thereof. US20180000819A1.
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