cyt-PTPε Inhibitor-1 |
رقم الكتالوجGC35791 |
Cyt-PTPε ؛ المانع -1 هو مثبط قوي للبروتين الخلوي التيروزين الفوسفاتيز إبسيلون (cyt-PTPε) ، ويرتبط بالمجال التحفيزي لـ cyt-PTPε ، ويمنع تنشيط c-Src (نزع الفسفرة من c-Src) ، ويعرض نشاطًا مضادًا لتورم العظام.
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Cas No.: 428478-94-8
Sample solution is provided at 25 µL, 10mM.
cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity[1]. cyt-PTPε[1]
cyt-PTPε Inhibitor-1 (Compound 62) is a potent cytosolic protein tyrosine phosphatase epsilon with anti-osteoclastic activity[1].
[1]. Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211.
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(Based on Reviews and 40 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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