Loxoprofen |
رقم الكتالوجGC36482 |
Loxoprofen هو عامل مضاد للالتهابات غير ستيرويدي نشط عن طريق الفم وله خصائص مسكنة ومضادة للحرارة
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Cas No.: 68767-14-6
Sample solution is provided at 25 µL, 10mM.
Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. COX-1|6.5 μM (IC50, in human whole blood)|COX-2|13.5 μM (IC50, in human whole blood)
[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.
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