TAS4464 hydrochloride |
| رقم الكتالوجGC37743 |
TAS4464 (هيدروكلوريد) هو مثبط قوي وانتقائي للغاية لإنزيم تنشيط NEDD8 (NAE) ، مع IC50 من 0.955 نانومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1848959-11-4
Sample solution is provided at 25 µL, 10mM.
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TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1]. IC50:0.955 nM (NAE)[1]
[1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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