T-1105 |
| رقم الكتالوجGC38244 |
يعتبر T-1105 ، وهو نظير هيكلي لـ T-705 ، مثبطًا جديدًا للبوليميراز الفيروسي واسع الطيف
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 55321-99-8
Sample solution is provided at 25 µL, 10mM.
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T-1105, a novel broad-spectrum viral polymerase inhibitor, structural analogue of T-705, inhibits the polymerases of RNA viruses after being converted to ribonucleoside triphosphate (RTP) metabolite[1]. T-1105 has antiviral activity against various RNA viruses, including Zika virus (ZIKV), influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), and foot-and-mouth disease virus (FMDV). T-1105 can be formed by nicotinamide mononucleotide adenylyltransferase[2].
[1]. Huchting J, et al. Cell line-dependent activation and antiviral activity of T-1105, the non-fluorinated analogue of T-705 (favipiravir). Antiviral Res. 2019 Jul;167:1-5. [2]. Furuta Y, et al. T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res. 2009 Jun;82(3):95-102.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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