GSK2578215A |
| رقم الكتالوجGC18049 |
GSK2578215A هو مثبط LRRK2 قوي وانتقائي للغاية ، والذي يعرض IC50s بحوالي 10 نانومتر ضد كل من LRRK2 من النوع البري و G2019S متحولة
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Cas No.: 1285515-21-0
Sample solution is provided at 25 µL, 10mM.
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GSK2578215A is a potent and highly selective LRRK2 inhibitor, which exhibits IC50s of around 10 nM against both wild-type LRRK2 and the G2019S mutant.
References:
[1]. Reith AD, et al. GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5625-9.
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