MI 14 |
رقم الكتالوجGC50216 |
Potent and selective PI 4-kinase IIIβ inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1715934-43-2
Sample solution is provided at 25 µL, 10mM.
Potent and selective PI 4-K IIIβ inhibitor (IC50 = 54 nM). Exhibits >1,800-fold selectivity for PI 4-K IIIβ over PI 4-K IIIα and PI 4-K IIα, respectively. Exhibits antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays.
Mejdrová et al (2015) Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action. J.Med.Chem. 58 3767 PMID:25897704
Average Rating: 5
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