T338C Src-IN-1 |
| رقم الكتالوجGC33168 |
T338C Src-IN-1 هو مثبط قوي متحولة- Src T338C ؛ أظهر تثبيطًا أقوى لـ T338C (IC50 = 111 نانومتر) بالنسبة إلى WT c-Src (زيادة بمقدار 10 أضعاف)
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Cas No.: 1351926-90-3
Sample solution is provided at 25 µL, 10mM.
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T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.
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