Trimethoprim N-oxide (Synonyms: Trimethoprim 1-N-oxide) |
رقم الكتالوجGC61353 |
ينتمي Trimethoprim N-oxide (Trimethoprim 1-N-oxide) إلى المستقلبات البولية البشرية
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Cas No.: 27653-68-5
Sample solution is provided at 25 µL, 10mM.
Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes[1].
[1]. Goldman JL, et al. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015 Sep;43(9):1372-80.
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