Reversan (Synonyms: CBLC4H10) |
| رقم الكتالوجGC12523 |
MST-312 هو أحد مثبطات الإنزيم تيلوميرازMST-312 هو مشتق معدل كيميائيا من الشاي الأخضر epigallocatechin gallate (EGCG)يمكن استخدام MST-312 في البحث عن السرطان ، مثل المايلوما المتعددة (MM)
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Cas No.: 313397-13-6
Sample solution is provided at 25 µL, 10mM.
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Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2].
References:
[1]. Tivnan A, et al. Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme. Front Neurosci. 2015 Jun 16;9:218.
[2]. Burkhart CA, et al. Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma. Cancer Res. 2009 Aug 15;69(16):6573-80.
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