Roflumilast-d4 |
| رقم الكتالوجGC48057 |
An internal standard for the quantification of roflumilast
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1398065-69-4
Sample solution is provided at 25 µL, 10mM.
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Roflumilast-d4 is intended for use as an internal standard for the quantification of roflumilast by GC- or LC-MS. Roflumilast is a potent, cell-permeable inhibitor of PDE4 (IC50 = <1 nM for both human PDE4B and PDE4D).1 It is selective for PDE4, with IC50 values against other PDE forms being greater than 10 μM.
1.Card, G.L., England, B.P., Suzuki, Y., et al.Structural basis for the activity of drugs that inhibit phosphodiesterasesStructure12(12)2233-2247(2004)
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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