RR-Src (trifluoroacetate salt) (Synonyms: Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly, RRLIEDAEYAARG, Src-Peptide) |
| رقم الكتالوجGC48332 |
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
RR-Src is a synthetic peptide substrate that corresponds to the sequence in Src surrounding the tyrosine subject to phosphorylation.1,2 It is a substrate for EGF-mediated tyrosine phosphorylation.3 RR-Src inhibits IL-2-induced proliferation of cytotoxic T cells.4
1.Casnellie, J.E., Harrison, M.L., Pike, L.J., et al.Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate fraction of a lymphoma cell lineProc. Natl. Acad. Sci. USA79(2)282-286(1982) 2.Pike, L.J., Gallis, B., Casnellie, J.E., et al.Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranesProc. Natl. Acad. Sci. USA79(5)1443-1447(1982) 3.Cassel, D., Pike, L.J., Grant, G.A., et al.Interaction of epidermal growth factor-dependent protein kinase with endogenous membrane proteins and soluble peptide substrateJ. Biol. Chem.258(5)2945-2950(1983) 4.Taffs, R.E., and Sitkovsky, M.V.Modulation of the effector functions of cytolytic T-lymphocytes with synthetic peptide inhibitors of protein kinasesJ. Pharm. Sci.81(1)37-44(1992)
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *