S961 acetate |
رقم الكتالوجGC61550 |
S961 أسيتات هو مضاد لمستقبلات الأنسولين الانتقائي عالي التقارب (IR) مع IC50s من 0.048 و 0.027 و 630 نانومتر لمستقبل HIR-A و HIR-B وعامل النمو الشبيه بالأنسولين البشري (HIGF-IR) في SPA -مقايسة على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1].
S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1].
[1]. SchÄffer L, et al. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14;376(2):380-3.
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