SIL Lipid |
| رقم الكتالوجGC91537 |
SIL lipid is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1566559-79-2
Sample solution is provided at 25 µL, 10mM.
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SIL lipid is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro.[1] LNPs containing SIL lipid and encapsulating siRNA targeting mRNA encoding the purinergic P2X7 receptor decrease protein levels of the purinergic P2X7 receptor, reduce migration in a wound healing assay, and induce apoptosis and necrosis in 4T1 breast cancer cells.
References:
[1].Kiaie, S.H., Zangi, A.R., Sheibani, M., et al.Novel synthesized ionizable lipid for LNP-mediated P2X7siRNA to inhibit migration and induce apoptosis of breast cancer cellsPurinergic Signal(2024).
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