SIRT5 inhibitor |
| رقم الكتالوجGC30251 |
مثبط SIRT5 هو مثبط قوي لإنزيم Sirtuin 5 deacylase البشري ، مع IC50 من 0.11 μ ؛ M.
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Cas No.: 2166487-21-2
Sample solution is provided at 25 µL, 10mM.
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SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
SIRT5 inhibitor (compound 49) is a very potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM, >100-fold from compound 1[1].
[1]. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841.
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