الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>Suberic acid-d4

Suberic acid-d4

رقم الكتالوجGC72563

Suberic acid-d4 هو الديوتيريوم المسمى بحمض سوبيريك.

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Suberic acid-d4 التركيب الكيميائي

Cas No.: 19031-57-3

الحجم السعر المخزون الكميّة
5 mg
45٫00
متوفر
10 mg
72٫00
متوفر
25 mg
144٫00
متوفر
50 mg
230٫00
متوفر
100 mg
360٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Suberic acid-d4 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Gregersen N, et al. General (medium-chain) acyl-CoA dehydrogenase deficiency (non-ketotic dicarboxylic aciduria): quantitative urinary excretion pattern of 23 biologically significant organic acids in three cases. Clin Chim Acta. 1983 Aug 15;132(2):181-91.

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