الصفحة الرئيسية>>Signaling Pathways>> Others>> Inhibitory Antibodies>>Tezepelumab

Tezepelumab

رقم الكتالوجGC72375

Tezepelumab (AMG 157) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor.

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Tezepelumab التركيب الكيميائي

Cas No.: 1572943-04-4

الحجم السعر المخزون الكميّة
1 mg
765٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Tezepelumab (AMG 157) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma.

Tezepelumab blocks thymic stromal lymphopoietin, an epithelial-cell-derived cytokine implicated in the pathogenesis of asthma[1].

References:
[1]. Menzies-Gow A, et, al. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809.

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