TFAP (Synonyms: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) |
| رقم الكتالوجGC19353 |
TFAP هو مثبط انتقائي لانزيمات الأكسدة الحلقية 1 (COX-1) ، مع IC 50 من 0.8 ميكرومتر
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Cas No.: 1011244-68-0
Sample solution is provided at 25 µL, 10mM.
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TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 uM.
TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 uM, while that against COX-2 is over 200 uM.
References:
[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.
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