الصفحة الرئيسية>>Signaling Pathways>> MAPK Signaling>> MEK1/2>>U0124

U0124

رقم الكتالوجGC15061

U0124 ، نظير U0126 غير نشط ، ليس له أي تأثير على مستويات البروتين c-Fos و c-Jun أو mRNAU0126 هو أحد مثبطات مجاهدي خلقلا يمنع U0124 مجاهدي خلق بتركيزات تصل إلى 100 ميكرومتر

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U0124 التركيب الكيميائي

Cas No.: 108923-79-1

الحجم السعر المخزون الكميّة
10mg
259٫00
Ship Within 7 Days

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  • GlpBio Citations

    GlpBio Citations
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Sample solution is provided at 25 µL, 10mM.

Chemical Properties of U0124

Cas No. 108923-79-1 SDF
Chemical Name (2Z,3Z)-2,3-bis(amino(methylthio)methylene)succinonitrile
Canonical SMILES N/C(SC)=C(C#N)\C(C#N)=C(N)\SC
Formula C8H10N4S2 M.Wt 226.31
الذوبان <22.63mg/ml in DMSO Storage Store at RT
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of U0124

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.4187 mL 22.0936 mL 44.1872 mL
5 mM 0.8837 mL 4.4187 mL 8.8374 mL
10 mM 0.4419 mL 2.2094 mL 4.4187 mL
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** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

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In vivo Formulation Calculator (Clear solution) of U0124

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for U0124

Average Rating: 5 ★★★★★ (Based on Reviews and 12 reference(s) in Google Scholar.)

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