Vicenin-1 |
| رقم الكتالوجGC61786 |
Vicenin 1 هو C-glycosylflavone له تأثير مثبط على الإنزيم المحول للأنجيوتنسين (ACE) (IC50 = 52.50 ميكرومتر)
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Cas No.: 35927-38-9
Sample solution is provided at 25 µL, 10mM.
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Vicenin 1 is a C-glycosylflavone isolated from the aerial parts of Desmodium styracifolium, has an inhibitory effect on angiotensin-converting enzyme (ACE)(IC50=52.50 μM)[1].
The target-isolated C-glycosylflavone (Vicenin 1) is evaluated for inhibitory activities. Vicenin 1 embodies effective ACE inhibitory activities with an IC50 value of 52.50 μM. The tested compound 3 (Vicenin 1) shows activity via the generation of chelate complexes within the active center of ACE[1].
[1]. Zhang YQ, et al. Bioassay-guided preparative separation of angiotensin-converting enzyme inhibitory C-flavone glycosides from Desmodium styracifolium by recycling complexation high-speed counter-current chromatography. J Pharm Biomed Anal. 2015 Jan;102:276-81.
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