الصفحة الرئيسية>>Volagidemab

Volagidemab

رقم الكتالوجGC72379

Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb).

Products are for research use only. Not for human use. We do not sell to patients.

Volagidemab التركيب الكيميائي

Cas No.: 1233956-13-2

الحجم السعر المخزون الكميّة
1 mg
270٫00
متوفر
5 mg
702٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D).

Volagidemab (5 mg/kg, s.c.) suppresses type 1 diabetes phenotype in Alloxan-induced diabetic mice[2].

References:
[1]. Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099.
[2]. Wang MY, et al. Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2503-8.

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