VU0071063 |
| رقم الكتالوجGC18629 |
VU0071063 عبارة عن فتاحة Kir6.2 / SUR1 قوية ومحددة (EC50 = 7.44 ميكرومتر) ويمكن استخدامها لفحص Kir6.2 / SUR1 المعبر عنها في البنكرياس والدماغ
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 333415-38-6
Sample solution is provided at 25 µL, 10mM.
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VU0071063 is a potent and selective activator of the inward-rectifier potassium channel (Kir) 6.2 and sulfonylurea receptor (SUR) 1 (EC50 = 7 uM using whole cell patch clamp electrophysiology). It is selective for SUR1-containing Kir6.1 or Kir6.2 channels over SUR2A, Kir2.1, Kir2.2, Kir2.3, Kir3.1/3/2, and voltage-gated potassium channel 2.1. VU0071063 inhibits glucose-stimulated calcium entry in isolated mouse pancreatic β-cells.
Review for VU0071063
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
Review for VU0071063
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