VU0080241 |
رقم الكتالوجGC61851 |
VU0080241 هو مُعدِّل خيفي موجب (PAM) من النوع الفرعي لمستقبلات الجلوتامات الأيضية 4 (mGluR4) ، مع EC50 من 4.6 ميكرومتر
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Cas No.: 393845-24-4
Sample solution is provided at 25 µL, 10mM.
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 µM[1].
References:
[1]. Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.
Average Rating: 5
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