VU6015929 |
| رقم الكتالوجGC39301 |
VU6015929 هو مثبط قوي ، انتقائي وفعال لمجال القرص الثنائي 1/2 (DDR1 / 2) مع IC50s من 4.67 نانومتر و 7.39 نانومتر ، على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2442597-56-8
Sample solution is provided at 25 µL, 10mM.
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VU6015929 is a potent, selective and orally active dual discoidin domain receptor 1/2 (DDR1/2) inhibitor with IC50s of 4.67 nM and 7.39 nM, respectively. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production[1].
[1]. Daniel E. Jeffries, et al. Discovery of VU6015929: A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy. ACS Med. Chem. Lett. 2019.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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