WEB 2086 (Synonyms: WEB 2086) |
| رقم الكتالوجGC14161 |
WEB 2086 (WEB 2086) ، وهو مضاد قوي لعامل تنشيط الصفائح الدموية (PAF) ، يمنع ارتباط PAF بمستقبلات PAF البشرية مع Ki البالغ 9.9 نانومتر.
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Cas No.: 105219-56-5
Sample solution is provided at 25 µL, 10mM.
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Apafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM[1].
References:
[1]. Kato M, et al. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004 Aug;95(4):435-42.
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