WYC-209 |
| رقم الكتالوجGC34862 |
WYC-209 ، وهو رتينويد اصطناعي ، هو ناهض لمستقبلات حمض الريتينويك (RAR)يستحث WYC-209 موت الخلايا المبرمج بشكل أساسي عبر مسار كاسباس 3 (IC50 = 0.19 ميكرومتر لورم الميلانوما الفئران الخبيثة) ، وله تأثيرات طويلة المدى مع سمية قليلة
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2131803-90-0
Sample solution is provided at 25 µL, 10mM.
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WYC-209 is a synthetic retinoid, which inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 of 0.19 μM. The primary cellular target of WYC-209 is retinoic acid receptors (RARs)[1]. Retinoic acid receptors[1]
[1]. Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406.
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