Z-Pro-prolinal |
| رقم الكتالوجGC70710 |
Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) هو مثبط إندوبيبتيداز بروليل محدد، نشط عن طريق الفم (PREP) مع IC50 من 0.4 نانومتر لل PREP خنزيري.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 88795-32-8
Sample solution is provided at 25 µL, 10mM.
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Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) (100 mg/kg; p.o.; once) increases septal vasopressin content in rats[3].
References:
[1]. Tsuru D, et al. Thiazolidine derivatives as potent inhibitors specific for prolyl endopeptidase. J Biochem. 1988;104(4):580-586.
[2]. Kilpeläinen TP, et al. The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy. Biomed Pharmacother. 2020;128:110253.
[3]. Miura N, et al. Increase in the septal vasopressin content by prolyl endopeptidase inhibitors in rats. Neurosci Lett. 1995;196(1-2):128-130.
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