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Atuzabrutinib

Catalog No.GC70685

Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor.

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Atuzabrutinib Chemical Structure

Cas No.: 1581714-49-9

Size Price Stock Qty
10mM (in 1mL DMSO)
$620.00
In stock
1 mg
$207.00
In stock
5 mg
$522.00
In stock
10 mg
$882.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling.

PRN473 (20 mg/kg) significantly reduces intravascular crawling and neutrophil recruitment into inflamed tissue in a model of sterile liver injury, down to levels seen in Btk-deficient animals[1].

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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